We produced predictive models for estimating the impacts of building a modification to Regional Road 62 (known as “la Cisa”) in the municipalities of Villafranca and Povegliano Veronese in terms of traffic-induced pollution (acoustic and gaseous emissions) caused by the new section of road. We also carried out archaeological risk and landscape impact assessments and produced photo-realistic renderings to simulate the appearance of the places after the works.